How To Tell When You’re Over

You’re a former presidential candidate from one of the major political parties and a member of the Senate. You’ve called for a party-line vote on a major issue against the opposition, investing your reputation and your credibility into the effort. However, you can only convince half of your caucus to vote with you, and even half of those tell reporters what a stupid idea it was from the outset. What happens afterwards?
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Kerry: Am I done?
Yes, Senator, you’re done. We only wish you’d realize it. (h/t: The Corner)